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Holiday schedule

Our Patient Service Centers will be closed on Monday, May 27, 2024 for the Memorial Day holiday. Have a healthy, happy holiday.

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Additional hereditary cancer risk tests

Certain things make it more likely that cancers in a family are caused by a hereditary cancer syndrome, such as:

  • Many cases of the same type of cancer (especially if it is an uncommon or rare type of cancer)
  • Cancers occurring at younger ages than usual (typically cancer in someone younger than 50 years old)
  • More than 1 type of cancer in a single person (such as a person with both breast and ovarian cancer)
  • Cancers occurring in both of a pair of organs (such as both eyes, both kidneys, or both breasts)
  • Cancer occurring in the sex not usually affected (such as breast cancer in a male)
  • Cancer occurring in multiple generations (such as in a parent, child, and grandchild)

Additional hereditary cancer risk tests

Test name

Test code

GSP or CPT coding

FAQ

Lynch syndrome

Lynch Syndrome Panel (5 genes)
Detects pathogenic variants in the MLH1, MSH2, MSH6, PMS2, and EPCAM (del/dup only) genes

91461

81295, 81297, 81292, 81294, 81298, 81300, 81317, 81319, 81403

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Other cancer risks

Nevoid Basal Cell Carcinoma (NBCCS) (Gorlin) Syndrome Panel (PTCH1, SUFU)
Detects variants in PTCH1 and SUFU

38651

81479

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Tuberous Sclerosis Complex Panel (TSC1, TSC2)
Detects variants in TSC1 and TSC2

38661

81405, 81406 (x2), 81407

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Juvenile Polyposis Panel (BMPR1A, SMAD4)
Detects pathogenic and variants of unknown significance (VUS) in the BMPR1A and SMAD4 genes

94053

81405, 81406, 81479

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Hereditary cancer genetic testing guide

Download our hereditary cancer reference guide for an overview of our tests, genes included in each test, and associated cancers (gene association based on guidelines and internal data).
hereditary-chart-cta

Test codes may vary by location. Please contact your local laboratory for more information.

Components of panels may be ordered separately.

The CPT® codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Helping you understand test results

We have created reports to help you and your patients better understand hereditary cancer test results.
hereditary-cancer-cta-image-bottom

Only a patient’s treating physician can make diagnoses, prognostic or treatment decisions based on the knowledge of the patient, history and clinical/educational experience. Quest lab testing provides information for the physician to use in helping make such decisions.